Details:
USP Name:Copovidone
EP Name:Copovidonum
Molecular Structure:
Chemical Name：Vinylpyrrolidone and vinyl acetate copolymer,Copovidone
INCI/CTFA Name:VP/VA Copolymer
CAS NO.:25086-89-9
Properties:
White or creamy white,free-flowing power with characteristic smell,hygroscopic.Soluble in water,alcohol and other organic solvents.
Quality Standard:Ph.EP.,USP/NF.
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Appearance
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White or creamy white,free-flowing power
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Aldehyde ppm max
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500
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Peroxide ppm max
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400
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Hydrazine ppm max
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1
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Monomers %max
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0.1
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2-Pyrrolidone %max
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0.5
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Heavy metal ppm max
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20
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Moisture %max
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5
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Sulphate ash %max
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0.1
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K value
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25.2-30.8
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VA content %
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35.3-42
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Nitrogen content %
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7.0-8.0
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Applications:
It possesses excellent adhesiveness,flexibility,forms a hard film and other characters,mainly used as a water-soluble binder and dry binder when used in wet granulation and direct compression tablet processes,also used as a film-forming material in film coatings.
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- Binding agent:used in wet granulation processes.
- Dry binding agent:used in direct compression tablet processes.
- Film coating agent:used for film promoters and sugar coating to prevent splitting,bottom binder to prevent moisture sensitivity.
- Crazing agent:acts in taste preparating and coating films.
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